Older people are more at risk of adverse drug reactions (ADRs) due to increased polypharmacy, and pharmacokinetic and pharmacodynamic changes. Common adverse reactions include confusion and delirium. ADRs account for five to 17 per cent of hospital admissions and increase the length of stay in about a quarter of hospital inpatients.
In older people, most ADRs are dose-dependent and predictable. However, many remain undiagnosed as they present with vague and nonspecific symptoms. It's therefore important to take a thorough medicines history for older patients presenting with new symptoms.
Identify a recent situation in which an older person has been prescribed six or more medicines. Do you think the use of all medicines is justified? What role can you play in identifying problematic polypharmacy?